Description

Pyrazolo[1,5-A]Pyrimidine-3,6-Dicarboxylic Acid 6-Ethyl Ester is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical discovery and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive pyrazolopyrimidine core.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, high-value heterocyclic scaffolds.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-3,6-Dicarboxylic Acid 6-Ethyl Ester
CAS No.	1408074-97-4
Molecular Formula	C11H9N3O4
Molecular Weight	247.21 g/mol
Synonyms	6-Ethyl Pyrazolo[1,5-a]pyrimidine-3,6-dicarboxylate; 6-Ethyl 3,6-dicarboxylatepyrazolo[1,5-a]pyrimidine; Ethyl 6-oxo-1,6-dihydropyrazolo[1,5-a]pyrimidine-3-carboxylate (tautomeric form); Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 3-carboxy-, ethyl ester; PPDE; 1408074-97-4; CAS 1408074-97-4
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyrimidine-3,6-Dicarboxylic Acid 6-Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP development and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from strong light sources. Keep away from strong alkalis and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.