Description

Methyl 7-(Trifluoromethyl)-1-Benzofuran-2-Carboxylate CAS NO 1407521-92-9 is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in the trifluoromethyl-substituted benzofuran scaffold, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzofuran core.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Product Name	Methyl 7-(Trifluoromethyl)-1-Benzofuran-2-Carboxylate
CAS No.	1407521-92-9
Molecular Formula	C11H7F3O3
Molecular Weight	244.17 g/mol
Synonyms	Methyl 7-(trifluoromethyl)benzofuran-2-carboxylate; 7-(Trifluoromethyl)-1-benzofuran-2-carboxylic acid methyl ester; 2-Benzofurancarboxylic acid, 7-(trifluoromethyl)-, methyl ester; Methyl 7-trifluoromethyl-1-benzofuran-2-carboxylate; 7-Trifluoromethylbenzofuran-2-carboxylic acid methyl ester; 1-Benzofuran-2-carboxylic acid, 7-(trifluoromethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 7-(Trifluoromethyl)-1-Benzofuran-2-Carboxylate is produced and tested under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible research and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profile is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.