Description

2-Chloro-3-Iodo-5-Methyl-1,6-Naphthyridine is a high-value, multi-functional halogenated naphthyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine and iodine substituents on the fused heterocyclic ring system, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, catalyst development, and the creation of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a probe or a tagged molecule in biochemical and pharmacological research studies.
• Cross-Coupling Reactions: The iodine and chlorine atoms make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	2-Chloro-3-Iodo-5-Methyl-1,6-Naphthyridine
CAS No.	1407521-91-8
Molecular Formula	C9H6ClIN2
Molecular Weight	304.51 g/mol
Synonyms	2-Chloro-3-iodo-5-methyl-1,6-naphthyridine; 5-Methyl-2-chloro-3-iodo-1,6-naphthyridine; 1,6-Naphthyridine, 2-chloro-3-iodo-5-methyl-; 1407521-91-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Iodo-5-Methyl-1,6-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. For research and commercial-scale projects requiring specific purity grades (e.g., >97%, >98%, >99%), please contact our technical sales team for the relevant specification sheet.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.