Description

Ethyl 4-Chloro-5-(Trifluoromethyl)-Pyridine-2-Carboxylate is a high-value pyridine derivative and a crucial synthetic intermediate in modern organic chemistry. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a building block for creating specialty chemicals, liquid crystals, and functional polymers with specific electronic or optical properties.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and enzyme inhibitors for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Ethyl 4-Chloro-5-(Trifluoromethyl)-Pyridine-2-Carboxylate
CAS No.	1407516-45-3
Molecular Formula	C9H7ClF3NO2
Molecular Weight	253.60 g/mol
Synonyms	Ethyl 4-chloro-5-(trifluoromethyl)picolinate; 4-Chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid ethyl ester; 2-Pyridinecarboxylic acid, 4-chloro-5-(trifluoromethyl)-, ethyl ester; Ethyl 4-chloro-5-trifluoromethylpyridine-2-carboxylate; 1407516-45-3; Ethyl 4-chloro-5-(trifluoromethyl)-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-Chloro-5-(Trifluoromethyl)-Pyridine-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.