Description

1-(6-Chloro-5-Iodo-2-Methylpyridin-3-Yl)Ethan-1-One is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials. The precise substitution pattern on the pyridine ring offers unique reactivity for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a key building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis, enabling challenging cross-coupling and functionalization reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive components for OLEDs and sensors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in university and corporate research laboratories focusing on heterocyclic chemistry.

Basic Information

Product Name	1-(6-Chloro-5-Iodo-2-Methylpyridin-3-Yl)Ethan-1-One
CAS No.	1407516-42-0
Molecular Formula	C8H7ClINO
Molecular Weight	295.51 g/mol
Synonyms	1-(6-Chloro-5-iodo-2-methyl-3-pyridinyl)ethanone; 6-Chloro-5-iodo-2-methyl-3-acetylpyridine; Ethanone, 1-(6-chloro-5-iodo-2-methyl-3-pyridinyl)-; 3-Acetyl-6-chloro-5-iodo-2-methylpyridine; 1-(6-Chloro-5-iodo-2-methylpyridin-3-yl)ethan-1-one; 2-Methyl-3-acetyl-6-chloro-5-iodopyridine
EINECS	Contact for details

Quality Control

Our 1-(6-Chloro-5-Iodo-2-Methylpyridin-3-Yl)Ethan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates, including those under development for regulatory submission.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider maintaining the product under an inert gas (argon or nitrogen) atmosphere. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.