Description

2-Pyridinemethanamine, 5-Bromo-n-(1,1-Dimethylethyl)- is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core with a tert-butyl-protected amine functional group. This compound is specifically engineered to serve as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce targeted bromine substitution and amine functionality into novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Pyridinemethanamine, 5-Bromo-n-(1,1-Dimethylethyl)-
CAS No.	1406786-33-1
Molecular Formula	C10H15BrN2
Molecular Weight	243.15 g/mol
Synonyms	5-Bromo-N-(tert-butyl)pyridin-2-ylmethanamine; N-(tert-Butyl)-1-(5-bromopyridin-2-yl)methanamine; 1-(5-Bromopyridin-2-yl)-N-(tert-butyl)methanamine; 5-Bromo-2-((tert-butylamino)methyl)pyridine; tert-Butyl-(5-bromopyrid-2-ylmethyl)amine; (5-Bromo-2-pyridylmethyl)-tert-butylamine; 2-((tert-Butylamino)methyl)-5-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-Pyridinemethanamine, 5-Bromo-n-(1,1-Dimethylethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.