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1,3,4,6-Tetra-o-Acetyl-2-[(2-Azidoacetyl)Amino]-2-Deoxy-β-D-Galactopyranose CAS NO 1404472-50-9


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CAS No.:1404472-50-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3,4,6-Tetra-o-Acetyl-2-[(2-Azidoacetyl)Amino]-2-Deoxy-β-D-Galactopyranose is a key protected glycosyl donor and advanced intermediate in carbohydrate chemistry. This compound is specifically engineered for the synthesis of complex oligosaccharides and glycoconjugates, offering precise control over glycosidic bond formation. It is an essential building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel glycotherapeutics, vaccines, and diagnostic agents. Its protected azidoacetyl group provides a versatile handle for further functionalization via click chemistry.

Application

  • Glycoconjugate Synthesis: A critical intermediate for the preparation of tumor-associated carbohydrate antigens (TACAs) and other biologically active glycoconjugates.
  • Pharmaceutical Research: Used in the development of novel glycoprotein-based drugs, antiviral agents, and vaccine candidates.
  • Click Chemistry Substrate: The azido group serves as a reliable partner for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to attach fluorophores, biotin, or other functional moieties.
  • Oligosaccharide Assembly: A protected galactosamine donor for automated or manual solid-phase and solution-phase oligosaccharide synthesis.
  • Chemical Biology Probes: Enables the creation of probes for studying carbohydrate-protein interactions, glycosylation pathways, and cell surface labeling.
  • Diagnostic Reagent Development: Serves as a precursor for synthesizing components of diagnostic kits and assays targeting specific carbohydrate biomarkers.

Basic Information

Product Name 1,3,4,6-Tetra-o-Acetyl-2-[(2-Azidoacetyl)Amino]-2-Deoxy-β-D-Galactopyranose
CAS No. 1404472-50-9
Molecular Formula C₁₆H₂₂N₄O₁₀
Molecular Weight 430.37 g/mol
Synonyms 2-Azidoacetamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-galactopyranose; 2-Deoxy-2-[(2-azidoacetyl)amino]-1,3,4,6-tetra-O-acetyl-β-D-galactopyranose; β-D-Galactopyranose, 2-[(2-azidoacetyl)amino]-2-deoxy-, 1,3,4,6-tetraacetate; Ac₄GalNAz; Tetraacetylated GalNAz; GalNAz(Ac)₄; 2-Azidoacetyl-GalNAc(Ac)₄; Peracetylated N-Azidoacetylgalactosamine
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical applications. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to strict quality management protocols to ensure batch-to-batch consistency and supply reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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