Description

tert-Butyl 1,9-Diazaspiro[4.6]Undecane-9-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Protease Inhibitor Development: The diazaspiro core is valuable for creating molecules that target specific proteases involved in disease pathways.
• Neurological Drug Synthesis: Employed in the research and development of potential treatments for neurological and psychiatric disorders.
• Chemical Biology Probes: Serves as a starting material for creating tools to study biological processes and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	tert-Butyl 1,9-Diazaspiro[4.6]Undecane-9-Carboxylate
CAS No.	1403767-18-9
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	1,9-Diazaspiro[4.6]undecane-9-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 1,9-diazaspiro[4.6]undecane-9-carboxylate; 9-Boc-1,9-diazaspiro[4.6]undecane; 1,9-Diazaspiro[4.6]undecane-9-carboxylic acid tert-butyl ester; Boc-1,9-diazaspiro[4.6]undecane; Spirocyclic Diamine Ester; 1,1-Dimethylethyl 1,9-diazaspiro[4.6]undecane-9-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 1,9-Diazaspiro[4.6]Undecane-9-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support customer requirements for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.