Description

tert-Butyl 2-(Aminomethyl)-1-Oxa-7-Azaspiro[3.5]Nonane-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel bioactive molecules. It is primarily sought after by pharmaceutical and biotechnology companies engaged in the synthesis of new chemical entities, particularly for central nervous system (CNS) and other therapeutic targets. The CAS number for this compound is 1403766-68-6.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its constrained spirocyclic structure.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional degrader molecules.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	tert-Butyl 2-(Aminomethyl)-1-Oxa-7-Azaspiro[3.5]Nonane-7-Carboxylate
CAS No.	1403766-68-6
Molecular Formula	C13H24N2O3
Molecular Weight	256.34 g/mol
Synonyms	7-Boc-2-(aminomethyl)-1-oxa-7-azaspiro[3.5]nonane; tert-Butyl 2-(aminomethyl)-1-oxa-7-azaspiro[3.5]nonane-7-carboxylate; 1-Oxa-7-azaspiro[3.5]nonane-7-carboxylic acid, 2-(aminomethyl)-, 1,1-dimethylethyl ester; 2-(Aminomethyl)-1-oxa-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; Boc-protected 2-aminomethyl-1-oxa-7-azaspiro[3.5]nonane; CAS 1403766-68-6
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(Aminomethyl)-1-Oxa-7-Azaspiro[3.5]Nonane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation from moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.