Description

1-Oxa-4,9-Diazaspiro[5.5]Undecan-3-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel therapeutic agents targeting central nervous system and other disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those with spirocyclic or bridged heterocyclic structures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Protease Inhibitor Development: The spirocyclic lactam core is a valuable motif in the design of enzyme inhibitors.
• Neurological Drug Discovery: Serves as a precursor for compounds targeting neurological pathways and receptors.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological processes and target validation.
• Custom Synthesis: Supplied for bespoke synthesis projects requiring high-purity, complex heterocyclic intermediates.

Basic Information

Item	Details
Product Name	1-Oxa-4,9-Diazaspiro[5.5]Undecan-3-One Hydrochloride
CAS No.	1402232-51-2
Molecular Formula	C9H15ClN2O2
Molecular Weight	218.68 g/mol
Synonyms	1-Oxa-4,9-diazaspiro[5.5]undecan-3-one, hydrochloride; 1-Oxa-4,9-diazaspiro[5.5]undecan-3-one HCl; 3-Oxo-1-oxa-4,9-diazaspiro[5.5]undecane hydrochloride; Spirocyclic lactam hydrochloride; 1-Oxa-4,9-diazaspiro[5.5]undecane-3-one hydrochloride; 1402232-51-2; UNII-7K5V2S6J2I (component)
EINECS	Contact for details

Quality Control

Our 1-Oxa-4,9-Diazaspiro[5.5]Undecan-3-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.