Description

Ethyl 3-Fluoro-4-Iodobutanoate is a high-value fluorinated and iodinated building block essential for advanced organic synthesis. This bifunctional compound is particularly significant for its role in introducing both fluorine and iodine atoms into target molecules, enabling precise structural modifications. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated and iodinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the introduction of fluorine can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with unique electronic or surface properties.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form carbon-carbon bonds.
• Fluorine Chemistry: Employed in nucleophilic substitution reactions to incorporate the fluorine atom into more complex molecular architectures.
• Labeling and Tracer Studies: Potential use in creating iodine-labeled compounds for diagnostic imaging or metabolic pathway tracing in research settings.

Basic Information

Item	Details
Product Name	Ethyl 3-Fluoro-4-Iodobutanoate
CAS No.	1401902-56-4
Molecular Formula	C6H10FIO2
Molecular Weight	260.05 g/mol
Synonyms	Ethyl 3-Fluoro-4-iodobutanoate; 3-Fluoro-4-iodobutanoic Acid Ethyl Ester; 4-Iodo-3-fluorobutanoic Acid Ethyl Ester; Butanoic acid, 3-fluoro-4-iodo-, ethyl ester; Ethyl 4-iodo-3-fluorobutanoate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Fluoro-4-Iodobutanoate is manufactured under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.