Description

4"-Hydroxy Rac-Kavain is a synthetic derivative of the natural kavalactone, kavain, featuring a hydroxyl group at the 4" position of the racemic compound. This modification is significant for researchers investigating the structure-activity relationships of kavalactones, particularly their interaction with central nervous system targets. It serves as a critical reference standard and intermediate for pharmaceutical and nutraceutical R&D, enabling the development of novel therapeutic agents and analytical methods.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of kavalactone derivatives in drug development and quality control laboratories.
• Neuroscience Research: A key compound for studying the pharmacological effects of kavain analogs on GABA receptors and other neurological pathways.
• Nutraceutical Ingredient Development: Serves as a precursor or model compound for formulating advanced dietary supplements targeting relaxation and cognitive support.
• Metabolite Studies: Employed in pharmacokinetic and metabolic profiling to understand the biotransformation of kavain in biological systems.
• Chemical Synthesis Intermediate: Utilized in organic synthesis to create novel libraries of kavalactone derivatives for high-throughput screening.
• Analytical Method Development: Essential for calibrating equipment and validating HPLC, LC-MS, or GC-MS methods in analytical chemistry.

Basic Information

Product Name	4"-Hydroxy Rac-Kavain
CAS No.	1401441-87-9
Molecular Formula	C₁₄H₁₄O₄
Molecular Weight	246.26 g/mol
Synonyms	4"-Hydroxy Racemic Kavain; (±)-4"-Hydroxykavain; 4"-OH-Kavain; 5,6-Dihydro-4"-hydroxykavain; 2-Methoxy-4-(4"-hydroxystyryl)-2H-pyran-6-one; Rac-4"-Hydroxykavain; 4"-Hydroxykavain (racemic)
EINECS	Contact for details

Quality Control

Our 4"-Hydroxy Rac-Kavain is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.