Description

2-[(9R)-9-(Pyridin-2-Yl)-6-Oxaspiro[4.5]Decan-9-Yl]Acetaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and pyridine-containing molecular architecture. This compound is of significant value for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly within medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, where precise stereochemistry and molecular complexity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or anti-infective targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for candidate drugs during preclinical and clinical development phases.
• Asymmetric Synthesis: Leverages its defined (9R) stereocenter for the construction of other enantiomerically pure compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of investigational new drugs.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and catalysis.

Basic Information

Product Name	2-[(9R)-9-(Pyridin-2-Yl)-6-Oxaspiro[4.5]Decan-9-Yl]Acetaldehyde
CAS No.	1401031-28-4
Molecular Formula	C16H21NO2
Molecular Weight	259.35 g/mol
Synonyms	(9R)-9-(2-Pyridinyl)-6-oxaspiro[4.5]decan-9-acetaldehyde; 2-[(9R)-9-(2-Pyridinyl)-6-oxaspiro[4.5]decan-9-yl]ethanal; (R)-2-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetaldehyde; 1401031-28-4; (9R)-9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-acetaldehyde; Spiro[4.5]decan-9-acetaldehyde, 9-(2-pyridinyl)-, (9R)-; 2-((9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetaldehyde
EINECS	Contact for details

Quality Control

Our production of 2-[(9R)-9-(Pyridin-2-Yl)-6-Oxaspiro[4.5]Decan-9-Yl]Acetaldehyde adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR for structural confirmation, and assays for chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be sensitive to prolonged exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.