Description

tert-Butyl 2-Azaspiro[3.3]Hept-6-Ylcarbamate Hemioxalate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in modern medicinal chemistry for the synthesis of novel bioactive molecules, particularly in central nervous system (CNS) and metabolic disorder research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its constrained spirocyclic structure.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Proteolysis Targeting Chimera (PROTAC) Development: Potential application as a linker or component in the design of bifunctional degrader molecules.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	tert-Butyl 2-Azaspiro[3.3]Hept-6-Ylcarbamate Hemioxalate
CAS No.	1400764-62-6
Molecular Formula	C14H24N2O5 • 0.5(C2H2O4)
Molecular Weight	Contact for details
Synonyms	tert-Butyl 2-azaspiro[3.3]heptane-6-carbamate hemioxalate; 2-Azaspiro[3.3]heptane-6-carboxylic acid, 1,1-dimethylethyl ester, hemioxalate; 6-((tert-Butoxycarbonyl)amino)-2-azaspiro[3.3]heptane oxalate (1:0.5); Boc-2-azaspiro[3.3]hept-6-ylamine hemioxalate; tert-Butyl N-(2-azaspiro[3.3]hept-6-yl)carbamate hemioxalate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Azaspiro[3.3]Hept-6-Ylcarbamate Hemioxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.