Description

1-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine core substituted with chloro and trifluoromethyl groups. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of agrochemicals and small-molecule therapeutics. It is primarily needed by research institutions and manufacturing facilities in the pharmaceutical and agrochemical industries seeking to develop new products with enhanced efficacy and specificity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the biological activity of the trifluoromethylpyridine moiety.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Preparation: Can be utilized to synthesize specialized ligands for metal catalysis or as a precursor for functionalized materials.

Basic Information

Product Name	1-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine Hydrochloride
CAS No.	1396762-41-6
Molecular Formula	C8H7ClF3N2•HCl
Molecular Weight	275.51 g/mol
Synonyms	1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine hydrochloride; 2-(1-Aminoethyl)-3-chloro-5-(trifluoromethyl)pyridine hydrochloride; Ethanamine, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-, hydrochloride; 1-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-ethylamine hydrochloride; α-Methyl-3-chloro-5-(trifluoromethyl)-2-pyridinemethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.