Description

1-Piperidinecarboxylic Acid, 4-Cyclopropylidene-, 1,1-Dimethylethyl Ester is a specialized piperidine derivative that serves as a high-value building block in advanced organic synthesis. Its unique structure, featuring a cyclopropylidene moiety, makes it a critical intermediate for constructing complex molecular architectures with specific stereochemical and functional properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and production of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the cyclopropylidene group for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Advanced Material Precursor: Potential intermediate in the synthesis of specialty polymers and ligands for catalytic systems.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for commercial active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-Cyclopropylidene-, 1,1-Dimethylethyl Ester
CAS No.	1395924-16-9
Molecular Formula	C13H21NO2
Molecular Weight	223.31 g/mol
Synonyms	tert-Butyl 4-cyclopropylidene-1-piperidinecarboxylate; 4-Cyclopropylidene-1-piperidinecarboxylic acid tert-butyl ester; 1-Boc-4-cyclopropylidenepiperidine; N-Boc-4-cyclopropylidenepiperidine; 1-(tert-Butoxycarbonyl)-4-cyclopropylidenepiperidine; 4-Cyclopropylidenepiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-cyclopropylidenepiperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-Cyclopropylidene-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.