Description

2-Fluoro-3-(1-Methylethoxy)-Benzoic Acid Methyl Ester is a high-value fluorinated aromatic ester building block, essential for advanced organic synthesis and pharmaceutical research. Its molecular structure, featuring a fluorine atom and an isopropoxy group, makes it a critical intermediate for constructing complex molecules with tailored biological activity and physicochemical properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Serves as a precursor for developing new herbicides, fungicides, and insecticides, leveraging the fluorine atom to enhance metabolic stability and bioavailability.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Intermediate for synthesizing advanced polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic units.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.
• Academic & Industrial R&D: Employed in research laboratories for method development, structure-activity relationship (SAR) studies, and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	2-Fluoro-3-(1-Methylethoxy)-Benzoic Acid Methyl Ester
CAS No.	1394964-61-4
Molecular Formula	C11H13FO3
Molecular Weight	212.22 g/mol
Synonyms	Methyl 2-Fluoro-3-isopropoxybenzoate; 2-Fluoro-3-isopropoxybenzoic Acid Methyl Ester; Benzoic acid, 2-fluoro-3-(1-methylethoxy)-, methyl ester; 3-Isopropoxy-2-fluorobenzoic Acid Methyl Ester; Methyl 3-Isopropoxy-2-fluorobenzoate; 1394964-61-4; 2-Fluoro-3-(isopropoxy)benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-(1-Methylethoxy)-Benzoic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.