Description

6-Chloro-1,3-Dihydro-5-Iodo-2H-Imidazo[4,5-B]Pyridine-2-Thione is a high-purity, heterocyclic organic compound with a unique fused ring structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile and functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the fields of oncology, antiviral agents, and other therapeutic areas requiring sophisticated heterocyclic cores.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting kinase inhibition or other protein-protein interactions.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and enzyme functions.
• Agrochemical Development: Potential intermediate in the research and synthesis of new generation pesticides or herbicides.
• Material Science Precursor: Can be utilized in the development of organic electronic materials or metal-organic frameworks (MOFs) due to its heteroatom-rich structure.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	6-Chloro-1,3-Dihydro-5-Iodo-2H-Imidazo[4,5-B]Pyridine-2-Thione
CAS No.	1394373-25-1
Molecular Formula	C6H3ClIN3S
Molecular Weight	311.53 g/mol
Synonyms	6-Chloro-5-iodo-2,3-dihydro-1H-imidazo[4,5-b]pyridine-2-thione; 2H-Imidazo[4,5-b]pyridine-2-thione, 6-chloro-1,3-dihydro-5-iodo-; 6-Chloro-5-iodo-1,3-dihydro-2H-imidazo[4,5-b]pyridine-2-thione; 1394373-25-1; AI3-63535; SCHEMBL21806227; ZINC000006039008; AKOS040759232
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,3-Dihydro-5-Iodo-2H-Imidazo[4,5-B]Pyridine-2-Thione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full spectroscopic data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.