Description

5-Chloro-6-Iodo-3-Nitropyridin-2-Amine is a high-purity, multi-functional halogenated nitropyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution, enabling diverse molecular architectures.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces.
• Dye & Pigment Intermediate: Potential use in the synthesis of complex, color-fast dyes and pigments due to its nitro and amine functionalities.

Basic Information

Product Name	5-Chloro-6-Iodo-3-Nitropyridin-2-Amine
CAS No.	1394373-21-7
Molecular Formula	C5H4ClIN3O2
Molecular Weight	315.46 g/mol
Synonyms	2-Amino-5-chloro-6-iodo-3-nitropyridine; 3-Nitro-5-chloro-6-iodopyridin-2-amine; 5-Chloro-6-iodo-3-nitro-2-pyridinamine; 2-Pyridinamine, 5-chloro-6-iodo-3-nitro-; 1394373-21-7
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Iodo-3-Nitropyridin-2-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality management system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.