Description

6-Chloro-5-Iodo-2-(Methylsulfonyl)-1H-Imidazo[4,5-B]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because its unique halogenated and sulfonated imidazopyridine core is critical for constructing complex molecules with targeted biological activity. It is primarily needed by pharmaceutical and agrochemical R&D teams for developing new active ingredients, as well as by academic and industrial researchers in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral programs.
• Medicinal Chemistry Scaffold: Used for structure-activity relationship (SAR) studies and library synthesis due to its versatile reactive sites for further functionalization.
• Agrochemical Research: Serves as a building block for the synthesis of new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Potential use in the synthesis of specialized organic electronic materials or ligands for catalysis.

Basic Information

Product Name	6-Chloro-5-Iodo-2-(Methylsulfonyl)-1H-Imidazo[4,5-B]Pyridine
CAS No.	1394373-18-2
Molecular Formula	C8H5ClIN3O2S
Molecular Weight	369.56 g/mol
Synonyms	6-Chloro-5-iodo-2-methylsulfonyl-1H-imidazo[4,5-b]pyridine; 2-(Methylsulfonyl)-6-chloro-5-iodo-1H-imidazo[4,5-b]pyridine; 1H-Imidazo[4,5-b]pyridine, 6-chloro-5-iodo-2-(methylsulfonyl)-; 1394373-18-2; 6-Chloro-5-iodo-2-(methanesulfonyl)-1H-imidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Iodo-2-(Methylsulfonyl)-1H-Imidazo[4,5-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.