Description

tert-Butyl 2,4-Dichloro-5,8-dihydro-1,7-naphthyridine-7(6H)-carboxylate is a high-value, functionalized naphthyridine derivative serving as a critical synthetic intermediate. Its molecular architecture, featuring a protected amine and reactive chloro substituents, makes it indispensable for constructing complex heterocyclic scaffolds. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including kinase inhibitors and other biologically relevant molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Intermediate for the synthesis of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	tert-Butyl 2,4-Dichloro-5,8-dihydro-1,7-naphthyridine-7(6H)-carboxylate
CAS No.	1393558-68-3
Molecular Formula	C13H14Cl2N2O2
Molecular Weight	301.17 g/mol
Synonyms	7-[(tert-Butoxy)carbonyl]-2,4-dichloro-5,8-dihydro-1,7-naphthyridine-6(7H)-carboxylate; 2,4-Dichloro-5,8-dihydro-7H-1,7-naphthyridine-7-carboxylic acid tert-butyl ester; tert-Butyl 2,4-dichloro-6,7-dihydro-5H-1,7-naphthyridine-7-carboxylate; 1393558-68-3; BOC-protected 2,4-dichloronaphthyridine; 2,4-Dichloro-7-Boc-5,6,7,8-tetrahydro-1,7-naphthyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,4-Dichloro-5,8-dihydro-1,7-naphthyridine-7(6H)-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.