Description

Methyl 3-[3-(Benzyloxy)Phenyl]-4-Fluorobenzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its specific substitution pattern enables precise molecular design. It is primarily needed by research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a fluorinated biphenyl-like scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom and aromatic system can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Acts as a building block for fluorinated mesogens and electron-transport materials, contributing to improved performance in display and lighting technologies.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, potentially altering thermal stability, solubility, and optical properties.
• Chemical Biology Probes: Utilized in the creation of fluorophore conjugates or labeled compounds for imaging and diagnostic assay development.
• Cross-Coupling Reactions: Functions as a substrate in Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions to construct more complex biaryl systems.

Basic Information

Product Name	Methyl 3-[3-(Benzyloxy)Phenyl]-4-Fluorobenzoate
CAS No.	1393441-85-4
Molecular Formula	C21H17FO3
Molecular Weight	336.36 g/mol
Synonyms	Methyl 3-(3-benzyloxyphenyl)-4-fluorobenzoate; 4-Fluoro-3'-(benzyloxy)-[1,1'-biphenyl]-3-carboxylic acid methyl ester; 3-[3-(Benzyloxy)phenyl]-4-fluorobenzoic acid methyl ester; Methyl 4-fluoro-3'-(phenylmethoxy)-[1,1'-biphenyl]-3-carboxylate; 3-(3-Benzyloxyphenyl)-4-fluorobenzoic Acid Methyl Ester; Benzene, 1,1'-[3-(fluoromethyl)-1,3-phenylenebisoxy]bis-, 1-methyl ester (non-standard); CAS 1393441-85-4
EINECS	Contact for details

Quality Control

Our production of Methyl 3-[3-(Benzyloxy)Phenyl]-4-Fluorobenzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analysis using advanced techniques including HPLC, GC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.