Description

(4R,5R)-3-tert-Butyl 4-Methyl 2,2,5-Trimethyloxazolidine-3,4-Dicarboxylate is a high-purity, chiral oxazolidine derivative that serves as a critical building block and chiral auxiliary in advanced organic synthesis. Its value lies in enabling the stereoselective construction of complex molecules, ensuring high enantiomeric purity in final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for process development and API synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand to induce stereoselectivity in catalytic reactions.
• Agrochemical Research: Used in the synthesis of novel, stereospecific pesticides and herbicides.
• Fine Chemical Production: Building block for creating complex natural products, flavors, and fragrances.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic and medicinal chemistry.
• Process Chemistry: Scalable intermediate for optimizing manufacturing routes for chiral compounds.

Basic Information

Product Name	(4R,5R)-3-tert-Butyl 4-Methyl 2,2,5-Trimethyloxazolidine-3,4-Dicarboxylate
CAS No.	1393440-06-6
Molecular Formula	C15H27NO5
Molecular Weight	301.38 g/mol
Synonyms	3-(tert-Butoxycarbonyl)-4-(methoxycarbonyl)-2,2,5-trimethyloxazolidine; (4R,5R)-3-Boc-4-COOMe-2,2,5-trimethyloxazolidine; (4R,5R)-2,2,5-Trimethyl-3-[(2-methylpropan-2-yl)oxycarbonyl]-4-(methoxycarbonyl)oxazolidine; (4R,5R)-3-(tert-Butoxycarbonyl)-4-(methoxycarbonyl)-2,2,5-trimethyloxazolidine; tert-Butyl (4R,5R)-4-(methoxycarbonyl)-2,2,5-trimethyloxazolidine-3-carboxylate; Chiral Oxazolidine Dicarboxylate Ester; Boc-Protected Oxazolidine Ester.
EINECS	Contact for details

Quality Control

Our (4R,5R)-3-tert-Butyl 4-Methyl 2,2,5-Trimethyloxazolidine-3,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.