Description

Methyl 1-Oxa-8-Azaspiro[4.5]Decane-2-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its value lies in its unique spirocyclic structure, which is a key motif in the development of novel bioactive molecules, particularly for central nervous system (CNS) and other therapeutic targets. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders.
• Organic Synthesis Reagent: Used in research laboratories for constructing complex spirocyclic and heterocyclic frameworks.
• Medicinal Chemistry Research: Serves as a key scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Employed in the scale-up and route scouting for the production of active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biological target identification and validation.

Basic Information

Product Name	Methyl 1-Oxa-8-Azaspiro[4.5]Decane-2-Carboxylate Hydrochloride
CAS No.	1392804-61-3
Molecular Formula	C10H17NO3 · HCl
Molecular Weight	235.71 g/mol
Synonyms	1-Oxa-8-azaspiro[4.5]decane-2-carboxylic acid, methyl ester, hydrochloride; Methyl 1-oxa-8-azaspiro[4.5]decane-2-carboxylate HCl; 8-Aza-1-oxaspiro[4.5]decane-2-carboxylic acid methyl ester hydrochloride; Methyl 8-aza-1-oxaspiro[4.5]decane-2-carboxylate hydrochloride; Spirocyclic oxazolidine ester hydrochloride; CAS 1392804-61-3
EINECS	Contact for details

Quality Control

Our Methyl 1-Oxa-8-Azaspiro[4.5]Decane-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.