Description

cis-Methyl 2,2-Dimethyl-3-Hydroxycyclobutanecarboxylate is a high-purity, functionalized cyclobutane derivative of significant interest in advanced organic synthesis. Its unique sterically constrained structure, featuring both a hydroxyl and an ester group, makes it a valuable chiral building block for the development of complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly those requiring rigid, functionalized ring systems.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cyclobutane scaffold can impart specific biological activity.
• Advanced Material Research: Serves as a monomer or precursor for specialty polymers and liquid crystals with tailored physical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development of new catalytic systems.
• Flavor & Fragrance Chemistry: Potential use in synthesizing complex odorants and flavoring agents with unique olfactory profiles.
• Academic & Industrial R&D: A versatile tool for methodological studies in organic chemistry, including ring-opening and functional group transformation reactions.

Basic Information

Product Name	cis-Methyl 2,2-Dimethyl-3-Hydroxycyclobutanecarboxylate
CAS No.	1392804-41-9
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Methyl cis-3-Hydroxy-2,2-dimethylcyclobutanecarboxylate; 3-Hydroxy-2,2-dimethylcyclobutanecarboxylic Acid Methyl Ester (cis-); (1r,3s)-3-Hydroxy-2,2-dimethylcyclobutanecarboxylic Acid Methyl Ester; cis-3-Hydroxy-2,2-dimethylcyclobutanecarboxylic Acid Methyl Ester; 2,2-Dimethyl-3-hydroxycyclobutanecarboxylic Acid Methyl Ester (cis-); Cyclobutanecarboxylic acid, 3-hydroxy-2,2-dimethyl-, methyl ester, cis-
EINECS	Contact for details

Quality Control

Our cis-Methyl 2,2-Dimethyl-3-Hydroxycyclobutanecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.