Description

6-Thia-1-Azaspiro[3.3]Heptane 6,6-Dioxide Hemioxalate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic sulfonamide scaffold. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve drug-like properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degraders.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds for studying enzyme function and biological pathways.
• CNS Drug Discovery: Employed in programs targeting receptors and enzymes within the central nervous system.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke organic synthesis projects at gram to kilogram scale.

Basic Information

Product Name	6-Thia-1-Azaspiro[3.3]Heptane 6,6-Dioxide Hemioxalate
CAS No.	1392804-12-4
Molecular Formula	C7H9NO6S
Molecular Weight	235.21 g/mol
Synonyms	1-Azaspiro[3.3]heptane-6-thia-6,6-dioxide hemioxalate; 6-Thia-1-azaspiro[3.3]heptane 6,6-dioxide oxalic acid salt (1:0.5); Azaspiro[3.3]heptane sulfone hemioxalate; Spiro[cyclopropane-1,1'-pyrrolidine]-2',2'-dioxide hemioxalate; 1-Oxa-6-thia-4-azaspiro[2.4]heptane 6,6-dioxide hemioxalate (related structure); 1392804-12-4; Pharmaceutical Intermediate 1392804-12-4
EINECS	Contact for details

Quality Control

Our 6-Thia-1-Azaspiro[3.3]Heptane 6,6-Dioxide Hemioxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.