Description

2-Ethynyl-5,8-Dioxaspiro[3.4]Octane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic ether and terminal alkyne functional group. This compound is valued for its role as a versatile building block in modern synthetic organic chemistry, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those requiring spirocyclic or strained ether scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its unique structure can impart specific biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored properties.
• Chemical Synthesis: Employed in click chemistry (e.g., CuAAC reactions) and other alkyne-based coupling strategies to create diverse compound libraries.
• Ligand & Catalyst Development: The alkyne and ether functionalities make it a useful precursor for creating novel ligands for metal catalysis.

Basic Information

Product Name	2-Ethynyl-5,8-Dioxaspiro[3.4]Octane
CAS No.	1392803-25-6
Molecular Formula	C8H8O2
Molecular Weight	136.15 g/mol
Synonyms	2-Ethynyl-5,8-dioxaspiro[3.4]octane; 5,8-Dioxaspiro[3.4]octane, 2-ethynyl-; Spiro[3.4]octane, 2-ethynyl-5,8-dioxa-; 2-Ethynyl-1,4-dioxaspiro[4.3]octane (related structural isomer); Terminal alkyne spirocyclic ether; Acetylene-functionalized spiroketal
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-5,8-Dioxaspiro[3.4]Octane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.