Description

cis-1-Azaspiro[4.5]Decan-8-Ol is a specialized spirocyclic amine alcohol building block of significant interest in advanced organic synthesis. Its unique rigid, three-dimensional structure makes it a valuable scaffold for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides, where its spirocyclic core can contribute to unique modes of action.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function and protein-ligand interactions.
• Ligand Development: Utilized in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: Employed in university and CRO settings for methodological development and exploring new chemical space.

Basic Information

Product Name	cis-1-Azaspiro[4.5]Decan-8-Ol
CAS No.	1392803-08-5
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	8-Hydroxy-1-azaspiro[4.5]decane (cis-); cis-8-Hydroxy-1-azaspiro[4.5]decane; 1-Azaspiro[4.5]decan-8-ol, cis-; Azaspirodecanol; Spirocyclic amino alcohol; Building block 1392803-08-5
EINECS	Contact for details

Quality Control

Every batch of cis-1-Azaspiro[4.5]Decan-8-Ol is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity (typically by HPLC or GC), chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.