Description

Ethyl (1S,3R,4R)4{[(Tertbutoxy)Carbonyl]Amino}3Hydroxycyclohexane1Carboxylate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel therapeutic agents, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in areas requiring sophisticated organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used in the design and construction of peptide analogs and conformationally constrained scaffolds for drug discovery.
• Asymmetric Synthesis: Serves as a crucial starting material or intermediate in stereoselective chemical reactions to introduce specific chiral centers.
• Protease Inhibitor Development: Found in the synthetic pathways for inhibitors targeting various proteolytic enzymes.
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of tool compounds and molecular probes for biological target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Ethyl (1S,3R,4R)4{[(Tertbutoxy)Carbonyl]Amino}3Hydroxycyclohexane1Carboxylate
CAS No.	1392745-47-9
Molecular Formula	C15H27NO5
Molecular Weight	301.38 g/mol
Synonyms	Ethyl (1S,3R,4R)-4-[(tert-Butoxycarbonyl)amino]-3-hydroxycyclohexane-1-carboxylate; (1S,3R,4R)-Ethyl 4-((tert-butoxycarbonyl)amino)-3-hydroxycyclohexanecarboxylate; Boc-4-amino-3-hydroxycyclohexanecarboxylic acid ethyl ester (specified stereoisomer); (1S,3R,4R)-4-(Boc-amino)-3-hydroxycyclohexanecarboxylic acid ethyl ester; Ethyl trans-4-[(tert-butoxycarbonyl)amino]-3-hydroxycyclohexanecarboxylate (1S,3R,4R); Boc-Ahch-OEt (stereospecific); Advanced Chiral Cyclohexane Derivative
EINECS	Contact for details

Quality Control

Our Ethyl (1S,3R,4R)4{[(Tertbutoxy)Carbonyl]Amino}3Hydroxycyclohexane1Carboxylate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and diastereomeric purity, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP synthesis. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere or in a desiccator to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.