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2-Azido-1,3-Bis[(2,2-Dimethyl-1,3-Dioxan-5-Yl)Oxy]Propane CAS NO 1392500-07-0
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CAS No.:1392500-07-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Azido-1,3-Bis[(2,2-Dimethyl-1,3-Dioxan-5-Yl)Oxy]Propane is a specialized bifunctional organic compound featuring azide and acetal-protected diol moieties. This unique structure makes it a valuable multifunctional linker and building block for advanced organic synthesis and materials science. It is primarily utilized by pharmaceutical researchers, polymer chemists, and bioconjugation specialists for constructing complex molecular architectures, including dendrimers, polymers, and targeted drug delivery systems.
Application
- Click Chemistry Reagent: Serves as a key precursor for Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition, CuAAC) reactions to create triazole linkages.
- Polymer & Dendrimer Synthesis: Acts as a core monomer or branching unit for the synthesis of functional polymers, cross-linked networks, and dendrimeric structures.
- Bioconjugation & Probe Development: Used to attach labels, drugs, or other functional groups to biomolecules (proteins, antibodies, oligonucleotides) via its reactive azide group.
- Pharmaceutical Intermediate: Employed in the research and development of novel active pharmaceutical ingredients (APIs) and prodrugs requiring specific linker chemistry.
- Material Science: Incorporated into surface modifications, hydrogels, and smart materials to introduce specific chemical functionality and reactivity.
- Ligand & Catalyst Scaffold: Provides a versatile scaffold for constructing multidentate ligands and immobilized catalysts.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2-Azido-1,3-Bis[(2,2-Dimethyl-1,3-Dioxan-5-Yl)Oxy]Propane |
| CAS No. | 1392500-07-0 |
| Molecular Formula | C15H27N3O6 |
| Molecular Weight | 345.39 g/mol |
| Synonyms | 1,3-Bis[(2,2-dimethyl-1,3-dioxan-5-yl)oxy]-2-azidopropane; 2-Azido-1,3-bis[(2,2-dimethyl-1,3-dioxolan-5-yl)oxy]propane (common isomer name); Azido-bis-acetal protected glycerol derivative; Bis(acetal) protected azido-glycerol; Multifunctional azido linker; Acetal-protected azido diol; Click chemistry building block |
| EINECS | Contact for details |
Quality Control
Our 2-Azido-1,3-Bis[(2,2-Dimethyl-1,3-Dioxan-5-Yl)Oxy]Propane is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid or low-melting solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Contact for higher grades) |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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