Description

tert-Butyl2-Oxo-1,3,7-Triazaspiro[4.4]Nonane-7-Carboxylate (Wx102677) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies and research institutions engaged in the development of new therapeutic agents, especially within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting protein-protein interactions.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel pharmacophores.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential component in the linker or ligand design for targeted protein degradation platforms.
• Kinase Inhibitor Synthesis: The spirocyclic structure is valuable for creating selective kinase inhibitors for cancer therapy.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke APIs for clinical trials.

Basic Information

Product Name	tert-Butyl2-Oxo-1,3,7-Triazaspiro[4.4]Nonane-7-Carboxylate (Wx102677)
CAS No.	1392207-76-9
Molecular Formula	C11H19N3O3
Molecular Weight	241.29 g/mol
Synonyms	7-Boc-2-oxo-1,3,7-triazaspiro[4.4]nonane; tert-Butyl 2-oxo-1,3,7-triazaspiro[4.4]nonane-7-carboxylate; 1,3,7-Triazaspiro[4.4]nonane-2-one, 7-(1,1-dimethylethyl) ester; WX-102677; Wx102677; 7-(tert-Butoxycarbonyl)-2-oxo-1,3,7-triazaspiro[4.4]nonane; 2-Oxo-1,3,7-triazaspiro[4.4]nonane-7-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl2-Oxo-1,3,7-Triazaspiro[4.4]Nonane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.