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3-Bromo-5-Isopropylphenylboronic Acid Pinacol Ester CAS NO 1392146-18-7
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CAS No.:1392146-18-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Bromo-5-Isopropylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences and advanced materials sectors for constructing complex molecular architectures.
Application
- Pharmaceutical Intermediates: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex biaryl structures.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
- Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
- Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
- Chemical Biology Probes: Useful in the synthesis of molecular probes for studying biological processes and target engagement.
- Academic and Industrial R&D: A fundamental tool for exploratory chemistry and process optimization in both university and corporate laboratory settings.
Basic Information
| Product Name | 3-Bromo-5-Isopropylphenylboronic Acid Pinacol Ester |
| CAS No. | 1392146-18-7 |
| Molecular Formula | C₁₅H₂₂BBrO₂ |
| Molecular Weight | 325.05 g/mol |
| Synonyms | (3-Bromo-5-isopropylphenyl)boronic acid pinacol ester; Pinacol (3-Bromo-5-isopropylphenyl)boronate; 5-Bromo-3-(propan-2-yl)phenylboronic acid pinacol ester; 3-Bromo-5-(1-methylethyl)benzeneboronic acid pinacol ester; Boronic acid, B-[3-bromo-5-(1-methylethyl)phenyl]-, 2,2-dimethyl-1,3-propanediyl ester; 3-Bromo-5-isopropylbenzeneboronic acid pinacol ester; 1392146-18-7 |
| EINECS | Contact for details |
Quality Control
Our 3-Bromo-5-Isopropylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR (¹H, ¹³C, ¹¹B), and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with our stringent specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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