Description

Octahydro-1H-Pyrrolo[3,4-C]Pyridin-1-One is a high-value, saturated bicyclic lactam building block of significant interest in advanced organic synthesis. Its rigid, nitrogen-containing scaffold makes it a crucial intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily utilized by pharmaceutical research and development organizations for the discovery and development of new active pharmaceutical ingredients (APIs), particularly in neurological and therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Building Block: Used to introduce a constrained, bicyclic lactam moiety into complex molecules, influencing their conformational and binding properties.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to enhance potency and selectivity.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study biological pathways and protein function.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents requiring specific heterocyclic frameworks.
• Catalyst Ligand Precursor: Can be modified to create novel ligands for asymmetric catalysis and metal-organic frameworks.

Basic Information

Product Name	Octahydro-1H-Pyrrolo[3,4-C]Pyridin-1-One
CAS No.	1391926-56-9
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	1-Azabicyclo[3.3.0]octan-2-one; Octahydropyrrolo[3,4-c]pyridin-1(2H)-one; 1,2,3,3a,4,5,6,7-Octahydro-1H-pyrrolo[3,4-c]pyridin-1-one; 2-Oxo-1-azabicyclo[3.3.0]octane; Bicyclic Lactam Intermediate
EINECS	Contact for details

Quality Control

Our Octahydro-1H-Pyrrolo[3,4-C]Pyridin-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.