Description

Benzyl 2,4-Dioxo-1,3,7-Triazaspiro[4.4]Nonane-7-Carboxylate CAS NO 1391828-70-8 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic triaza structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of next-generation drugs, including protease inhibitors and other targeted small-molecule therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel Active Pharmaceutical Ingredients (APIs).
• Protease Inhibitor Development: Serves as a core scaffold for designing and synthesizing potential protease inhibitors for antiviral or anticancer applications.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its spirocyclic and heterocyclic features.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule synthesis.
• Bioconjugation & Probe Synthesis: The benzyl ester group can be utilized for further chemical modifications to create biochemical probes or conjugate molecules.

Basic Information

Product Name	Benzyl 2,4-Dioxo-1,3,7-Triazaspiro[4.4]Nonane-7-Carboxylate
CAS No.	1391828-70-8
Molecular Formula	C14H15N3O4
Molecular Weight	289.29 g/mol
Synonyms	7-Benzyloxycarbonyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonane; Benzyl 1,3,7-triazaspiro[4.4]nonane-2,4-dione-7-carboxylate; 7-CBZ-2,4-dioxo-1,3,7-triazaspiro[4.4]nonane; Spirotriazinedione derivative; 1,3,7-Triazaspiro[4.4]nonane-2,4-dione, 7-(phenylmethyl) ester; Z-Protected Spirocyclic Triazinedione; CAS 1391828-70-8
EINECS	Contact for details

Quality Control

Our Benzyl 2,4-Dioxo-1,3,7-Triazaspiro[4.4]Nonane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.