Description

(S)-5',8'-Dimethoxy-3',4'-Dihydro-1'H-Spiro[Imidazolidine-4,2'-Naphthalene]-2,5-Dione is a high-purity, chiral spirocyclic compound of significant interest in advanced organic synthesis. This molecule serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors for creating complex molecular architectures with specific stereochemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce the (S)-configured spiro center into more complex molecules.
• Agrochemical Research: Serves as a starting material for developing new active ingredients with specific biological activity.
• Academic & Industrial R&D: Used in methodological studies and for exploring new chemical spaces in medicinal chemistry.
• Ligand & Catalyst Development: Potential framework for creating novel chiral ligands or organocatalysts.

Basic Information

Product Name	(S)-5',8'-Dimethoxy-3',4'-Dihydro-1'H-Spiro[Imidazolidine-4,2'-Naphthalene]-2,5-Dione
CAS No.	1391557-65-5
Molecular Formula	C₁₄H₁₆N₂O₄
Molecular Weight	276.29 g/mol
Synonyms	(S)-5',8'-Dimethoxy-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione; (S)-Spiro[imidazolidine-4,2'-naphthalene]-2,5-dione, 5',8'-dimethoxy-3',4'-dihydro-; (S)-5,8-Dimethoxy-3,4-dihydro-1H-spiro[naphthalene-2,4'-imidazolidine]-2',5'-dione; 1391557-65-5; (S)-enantiomer of the spirocyclic imidazolidinedione.
EINECS	Contact for details

Quality Control

Every batch of our (S)-5',8'-Dimethoxy-3',4'-Dihydro-1'H-Spiro[Imidazolidine-4,2'-Naphthalene]-2,5-Dione is manufactured under strict quality management systems. We perform comprehensive analytical testing, including chiral purity verification, to ensure the product meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.