Description

(R)-1-(2-Bromopyridin-4-Yl)Ethanamine Dihydrochloride is a high-purity chiral amine derivative, specifically the (R)-enantiomer, which serves as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with precise biological activity. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including kinase inhibitors and central nervous system (CNS) active drugs.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic and R&D: Used in university and institutional research laboratories for methodological studies in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	(R)-1-(2-Bromopyridin-4-Yl)Ethanamine Dihydrochloride
CAS No.	1391423-76-9
Molecular Formula	C7H10BrCl2N2
Molecular Weight	282.98 g/mol
Synonyms	(R)-1-(2-Bromo-4-pyridinyl)ethanamine dihydrochloride; (R)-1-(2-Bromopyridin-4-yl)ethan-1-amine dihydrochloride; (R)-1-(2-Bromopyridin-4-yl)ethylamine dihydrochloride; (R)-α-Methyl-2-bromo-4-pyridinemethanamine dihydrochloride; (R)-2-Bromo-4-(1-aminoethyl)pyridine dihydrochloride; (R)-1-(2-Bromo-4-pyridyl)ethylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our production of (R)-1-(2-Bromopyridin-4-Yl)Ethanamine Dihydrochloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to meet the exacting standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.