Description

Methyl (3S)-3-Amino-3-(4-Pyridyl)Propanoate Dihydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex molecules with high enantiomeric purity, leveraging the (3S) stereocenter.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for asymmetric transformations.
• Peptidomimetics Research: The amino acid ester structure makes it valuable for creating non-natural amino acid derivatives and peptidomimetic compounds.
• Agrochemical Synthesis: Employed in the development of advanced, chiral agrochemicals with improved efficacy and environmental profiles.
• Academic & Contract Research: A valuable reagent for academic research institutions and CROs (Contract Research Organizations) exploring new synthetic methodologies.

Basic Information

Product Name	Methyl (3S)-3-Amino-3-(4-Pyridyl)Propanoate Dihydrochloride
CAS No.	1391405-13-2
Molecular Formula	C9H12N2O2 · 2HCl
Molecular Weight	265.12 g/mol (as free base: 180.20 g/mol)
Synonyms	(3S)-3-Amino-3-(4-pyridinyl)propanoic acid methyl ester dihydrochloride; Methyl L-3-Amino-3-(4-pyridyl)propionate dihydrochloride; (S)-Methyl 3-amino-3-(pyridin-4-yl)propanoate dihydrochloride; 4-Pyridinepropanoic acid, 3-amino-, methyl ester, (3S)-, dihydrochloride; Methyl (S)-3-Amino-3-(4-pyridinyl)propanoate dihydrochloride; (S)-Methyl 3-amino-3-(4-pyridyl)propanoate hydrochloride (1:2); CAS 1391405-13-2
EINECS	Contact for details

Quality Control

Our Methyl (3S)-3-Amino-3-(4-Pyridyl)Propanoate Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.