Description

3-Methyl-1-Oxa-3,7-Diazaspiro[4.4]Nonan-2-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Serves as a critical starting material for optimizing scalable synthetic routes to potential APIs.
• Bioconjugation & Probe Synthesis: The reactive functional groups make it suitable for creating biochemical probes and targeted drug delivery systems.
• Academic & Industrial R&D: Employed in academic laboratories and corporate R&D departments for exploratory synthesis and new molecular entity development.

Basic Information

Product Name	3-Methyl-1-Oxa-3,7-Diazaspiro[4.4]Nonan-2-One Hydrochloride
CAS No.	1390655-03-4
Molecular Formula	C8H13N3O2 • HCl
Molecular Weight	219.66 g/mol (free base: 183.21 g/mol)
Synonyms	3-Methyl-1-oxa-3,7-diazaspiro[4.4]nonan-2-one hydrochloride; 1-Oxa-3,7-diazaspiro[4.4]nonan-2-one, 3-methyl-, hydrochloride; 3-Methyl-1-oxa-3,7-diazaspiro[4.4]nonane-2-one HCl; Spirocyclic oxazolidinone hydrochloride; 1390655-03-4
EINECS	Contact for details

Quality Control

Our 3-Methyl-1-Oxa-3,7-Diazaspiro[4.4]Nonan-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.