Description

[1,1'-Biphenyl]-3-Carboxylic Acid, 4'-Amino-2-Fluoro-, Methyl Ester is a high-purity, functionalized biphenyl derivative designed for advanced chemical synthesis. This compound is valued for its role as a critical building block in the development of complex organic molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate a fluorinated, amino-substituted biphenyl scaffold into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the biphenyl core and fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, where its rigid, conjugated structure is beneficial for charge transport and luminescent properties.
• Polymer Modification: Employed to introduce functional groups into polymer backbones, modifying thermal, mechanical, or optical characteristics for specialty plastics and coatings.
• Chemical Biology Probes: Utilized in the creation of fluorescent tags or molecular probes for studying biological pathways and protein interactions.
• Catalyst Ligand Synthesis: Provides a framework for constructing sophisticated ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	[1,1'-Biphenyl]-3-Carboxylic Acid, 4'-Amino-2-Fluoro-, Methyl Ester
CAS No.	1389287-35-7
Molecular Formula	C15H12FNO2
Molecular Weight	257.26 g/mol
Synonyms	4'-Amino-2-fluoro-[1,1'-biphenyl]-3-carboxylic acid methyl ester; Methyl 4'-amino-2-fluorobiphenyl-3-carboxylate; 2-Fluoro-4'-aminobiphenyl-3-carboxylic acid methyl ester; 3-(Methoxycarbonyl)-4'-amino-2-fluorobiphenyl; Biphenyl-3-carboxylic acid, 4'-amino-2-fluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-3-Carboxylic Acid, 4'-Amino-2-Fluoro-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.