Description

cis-tert-Butyl 3-Iodocyclobutylcarbamate CAS NO 1389264-12-3 is a high-purity, advanced pharmaceutical intermediate featuring a functionalized cyclobutane ring. This compound is valued for its role as a versatile building block in modern organic synthesis, particularly in the construction of complex, constrained molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those requiring a strained cyclobutane scaffold for biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with unique modes of action.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties.
• Methodology Development: Employed in academic and industrial research to develop new cross-coupling and C-H activation methodologies.
• Peptidomimetics: The carbamate-protected amine and iodine handle make it useful for constructing conformationally restricted peptide analogs.

Basic Information

Product Name	cis-tert-Butyl 3-Iodocyclobutylcarbamate
CAS No.	1389264-12-3
Molecular Formula	C9H16INO2
Molecular Weight	297.14 g/mol
Synonyms	tert-Butyl (1s,3s)-3-iodocyclobutylcarbamate; (1s,3s)-3-Iodocyclobutylcarbamic acid tert-butyl ester; cis-3-Iodocyclobutylamine tert-butyl carbamate; BOC-cis-3-iodocyclobutylamine; N-Boc-cis-3-iodocyclobutylamine; cis-N-Boc-3-iodocyclobutylamine; (1s,3s)-N-Boc-3-iodocyclobutylamine
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl 3-Iodocyclobutylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.