Description

Isopropyl (Z)-3-Iodoacrylate CAS NO 1388842-43-0 is a specialized, high-purity iodinated acrylate ester monomer. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce both an acrylate moiety and an iodine atom, which serves as a versatile handle for further functionalization. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting challenging disease pathways.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Polymer & Material Science: Serves as a functional monomer for creating specialty polymers with unique properties, such as light-responsive or self-healing materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form carbon-carbon bonds.
• Ligand & Catalyst Development: Employed in the synthesis of complex organic ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for labeling biomolecules or creating activity-based probes for studying enzymatic function.

Basic Information

Product Name	Isopropyl (Z)-3-Iodoacrylate
CAS No.	1388842-43-0
Molecular Formula	C6H9IO2
Molecular Weight	240.04 g/mol
Synonyms	(Z)-Isopropyl 3-iodoacrylate; (Z)-Isopropyl 3-iodoprop-2-enoate; Isopropyl (Z)-3-iodo-2-propenoate; (Z)-3-Iodoacrylic Acid Isopropyl Ester; 2-Propenoic acid, 3-iodo-, 1-methylethyl ester, (Z)-; 3-Iodoacrylic Acid Isopropyl Ester (Z-isomer)
EINECS	Contact for details

Quality Control

Every batch of Isopropyl (Z)-3-Iodoacrylate is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure high chemical and isomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee reproducible results for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Z-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.