Description

Methyl 4-Oxo-1-[3-(Trifluoromethyl)Phenyl]Cyclohexanecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethylphenyl-substituted cyclohexanecarboxylate structure. This compound is of significant commercial importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular frameworks. It is primarily sought after by research organizations, fine chemical manufacturers, and pharmaceutical companies engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug molecules, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Used in the development of advanced crop protection agents and herbicides due to its stable, functionalized ring system.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and aliphatic properties.
• Organic Synthesis: Employed in academic and industrial R&D for constructing complex organic molecules, especially those requiring the trifluoromethyl group for enhanced bioavailability or metabolic stability.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Methyl 4-Oxo-1-[3-(Trifluoromethyl)Phenyl]Cyclohexanecarboxylate
CAS No.	1385694-63-2
Molecular Formula	C15H15F3O3
Molecular Weight	300.28 g/mol
Synonyms	Methyl 1-[3-(trifluoromethyl)phenyl]-4-oxocyclohexanecarboxylate; 4-Oxo-1-[3-(trifluoromethyl)phenyl]cyclohexanecarboxylic acid methyl ester; 1-(3-(Trifluoromethyl)phenyl)-4-oxocyclohexanecarboxylic Acid Methyl Ester; Cyclohexanecarboxylic acid, 4-oxo-1-[3-(trifluoromethyl)phenyl]-, methyl ester; CAS 1385694-63-2
EINECS	Contact for details

Quality Control

Our Methyl 4-Oxo-1-[3-(Trifluoromethyl)Phenyl]Cyclohexanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we can support development projects requiring ICH stability guidelines or other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.