Description

(3β)-24-Bromo-3-[(tert-Butyl)Dimethylsilyloxy]-Chol-5-Ene CAS NO 1384736-07-5 is a high-purity, steroidal intermediate featuring a brominated side chain and a protected hydroxyl group. This compound is critically important for its role as a versatile building block in advanced organic synthesis, particularly for the development of novel pharmaceutical agents and bioactive molecules. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in steroid chemistry, drug discovery, and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel steroid-based therapeutics and hormone analogs.
• Drug Discovery Research: Used as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Chemical Synthesis: Serves as a protected and functionalized starting material for complex multi-step organic syntheses.
• Biochemical Research: Potential tool compound for studying steroid receptor interactions and metabolic pathways.
• Process Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals and advanced materials.

Basic Information

Product Name	(3β)-24-Bromo-3-[(tert-Butyl)Dimethylsilyloxy]-Chol-5-Ene
CAS No.	1384736-07-5
Molecular Formula	C₃₁H₅₃BrOSi
Molecular Weight	549.75 g/mol
Synonyms	24-Bromo-3β-[(tert-butyldimethylsilyl)oxy]cholest-5-ene; 3β-[(tert-Butyldimethylsilyl)oxy]-24-bromocholest-5-ene; (3β)-24-Bromo-3-[(tert-butyl)dimethylsilyloxy]cholest-5-ene; 24-Bromo-3β-TBDMS-cholest-5-ene; TBDMS-protected 24-bromocholesterol derivative; Steroid TBDMS ether bromide; Cholest-5-ene-3β-ol, 24-bromo-, 3-(tert-butyldimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support research and manufacturing needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.