Description

2-Oxa-7-Azaspiro[4.4]Nonan-8-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing seeking to develop new therapeutic candidates with improved properties.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery programs.
• CNS Drug Development: Used in the research and synthesis of potential therapeutics targeting neurological disorders.
• Antiviral Agent Synthesis: Serves as a structural component in the development of new antiviral compounds.
• Protease Inhibitor Scaffold: The spirocyclic structure is applicable in creating inhibitors for various enzymatic targets.
• Chemical Biology & Probe Development: Utilized for creating molecular tools to study biological pathways.
• Process Chemistry & Scale-Up: Employed in the optimization and commercial-scale production of candidate drugs.
• Academic & Institutional Research: Used in universities and research institutes for exploratory synthetic chemistry.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services.

Basic Information

Product Name	2-Oxa-7-Azaspiro[4.4]Nonan-8-One
CAS No.	1384427-76-2
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	8-Oxa-2-azaspiro[4.4]nonan-1-one; 2-Oxa-7-azaspiro[4.4]nonan-8-one; 1-Oxa-4-azaspiro[4.4]nonan-5-one; Spiro[oxolane-2,1'-pyrrolidin]-2'-one; 7-Azaspiro[4.4]nonane-8-one, 2-oxa-; 1384427-76-2; 2-Oxa-7-azaspiro[4.4]nonan-8-one
EINECS	Contact for details

Quality Control

Our 2-Oxa-7-Azaspiro[4.4]Nonan-8-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete batch data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.