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2-[(2-Azidoacetyl) Amino] -2-Deoxy-D-Glu- Copyranose CAS NO 1384117-59-2


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CAS No.:1384117-59-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[(2-Azidoacetyl) Amino] -2-Deoxy-D-Glu- Copyranose CAS NO 1384117-59-2 is a specialized carbohydrate derivative featuring an azidoacetyl functional group, making it a valuable click chemistry intermediate. This compound is engineered for advanced bioconjugation and glycobiology research, enabling precise labeling and modification of biomolecules. It is primarily utilized by pharmaceutical R&D teams and academic researchers developing novel diagnostics, targeted therapeutics, and chemical probes.

Application

  • Click Chemistry Reagent: Serves as a key intermediate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions in bioconjugation.
  • Glycoprotein Engineering: Used for the site-specific modification and labeling of glycoproteins and antibodies.
  • Probe Synthesis: A building block for creating fluorescent, affinity, or radiolabeled probes for cellular imaging and target identification.
  • Drug Discovery: Facilitates the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
  • Material Science: Applied in the surface functionalization of nanoparticles and polymers for biomedical applications.
  • Enzyme Inhibitor Studies: Acts as a precursor for synthesizing mechanism-based inhibitors of glycosidases or glycosyltransferases.

Basic Information

Product Name 2-[(2-Azidoacetyl) Amino] -2-Deoxy-D-Glu- Copyranose
CAS No. 1384117-59-2
Molecular Formula C8H12N4O7
Molecular Weight 276.20 g/mol
Synonyms 2-Deoxy-2-[(2-azidoacetamido)]-D-glucopyranose; N-Azidoacetylglucosamine; 2-Azidoacetamido-2-deoxy-D-glucose; GlcNAz derivative; Azidoacetyl-D-glucosamine; Click chemistry sugar; Azido-functionalized monosaccharide; 2-AADG
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Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. Our production follows cGMP guidelines where applicable, and each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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