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2-[(2-Azidoacetyl) Amino] -2-Deoxy-D-Glu- Copyranose CAS NO 1384117-59-2
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CAS No.:1384117-59-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-[(2-Azidoacetyl) Amino] -2-Deoxy-D-Glu- Copyranose CAS NO 1384117-59-2 is a specialized carbohydrate derivative featuring an azidoacetyl functional group, making it a valuable click chemistry intermediate. This compound is engineered for advanced bioconjugation and glycobiology research, enabling precise labeling and modification of biomolecules. It is primarily utilized by pharmaceutical R&D teams and academic researchers developing novel diagnostics, targeted therapeutics, and chemical probes.
Application
- Click Chemistry Reagent: Serves as a key intermediate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions in bioconjugation.
- Glycoprotein Engineering: Used for the site-specific modification and labeling of glycoproteins and antibodies.
- Probe Synthesis: A building block for creating fluorescent, affinity, or radiolabeled probes for cellular imaging and target identification.
- Drug Discovery: Facilitates the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
- Material Science: Applied in the surface functionalization of nanoparticles and polymers for biomedical applications.
- Enzyme Inhibitor Studies: Acts as a precursor for synthesizing mechanism-based inhibitors of glycosidases or glycosyltransferases.
Basic Information
| Product Name | 2-[(2-Azidoacetyl) Amino] -2-Deoxy-D-Glu- Copyranose |
| CAS No. | 1384117-59-2 |
| Molecular Formula | C8H12N4O7 |
| Molecular Weight | 276.20 g/mol |
| Synonyms | 2-Deoxy-2-[(2-azidoacetamido)]-D-glucopyranose; N-Azidoacetylglucosamine; 2-Azidoacetamido-2-deoxy-D-glucose; GlcNAz derivative; Azidoacetyl-D-glucosamine; Click chemistry sugar; Azido-functionalized monosaccharide; 2-AADG |
| EINECS | Contact for details |
Quality Control
We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. Our production follows cGMP guidelines where applicable, and each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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