Description

Ethanone, 1-(6-Bromo-1H-Pyrazolo[4,3-B]Pyridin-1-Yl)- is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1383735-65-6. This compound is a critical building block in modern medicinal chemistry, valued for its unique fused heterocyclic structure that enables the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies for novel drug candidates.
• Oncology Drug Development: Serves as a core scaffold for developing potential anti-cancer agents due to its pyrazolopyridine moiety.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	Ethanone, 1-(6-Bromo-1H-Pyrazolo[4,3-B]Pyridin-1-Yl)-
CAS No.	1383735-65-6
Molecular Formula	C8H6BrN3O
Molecular Weight	240.06 g/mol
Synonyms	1-(6-Bromo-1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone; 6-Bromo-1-(1H-pyrazolo[4,3-b]pyridin-1-yl)ethan-1-one; 6-Bromo-1H-pyrazolo[4,3-b]pyridin-1-yl methyl ketone; 1-Acetyl-6-bromo-1H-pyrazolo[4,3-b]pyridine; 1383735-65-6; Bromo Pyrazolopyridine Acetone Derivative
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(6-Bromo-1H-Pyrazolo[4,3-B]Pyridin-1-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere if long-term storage is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.