Description

4-(4-Nitrophenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific nitrophenyl-tetrahydropyridine structure. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for synthesizing novel drug candidates. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules for potential drug discovery programs, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Process Development: Employed in route scouting and optimization for the scalable synthesis of target active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for studying organic reaction mechanisms and developing new synthetic methodologies.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or tagged molecules for biochemical and pharmacological assays.

Basic Information

Product Name	4-(4-Nitrophenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride
CAS No.	1383706-16-8
Molecular Formula	C11H13ClN2O2
Molecular Weight	240.69 g/mol
Synonyms	4-(4-Nitrophenyl)-1,2,3,6-tetrahydropyridine HCl; 4-(p-Nitrophenyl)-1,2,3,6-tetrahydropyridine hydrochloride; 1,2,3,6-Tetrahydro-4-(4-nitrophenyl)pyridine hydrochloride; 4-(4-Nitrophenyl)-3,6-dihydro-2H-pyridine hydrochloride; 4-(4-Nitro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4-Nitrophenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.