Description

Ethyl 3-(Benzyloxycarbonylamino)-3-Methylbutanoate CAS NO 1381947-21-2 is a high-purity, protected amino acid ester derivative primarily used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors, where precise chemical functionality is paramount. It serves as an essential intermediate for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly those requiring protected amino acid motifs.
• Peptide Chemistry: Used in the preparation of modified peptides and peptidomimetics, where the Cbz (benzyloxycarbonyl) group acts as a temporary protecting group for the amine functionality.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific chiral centers.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing β-amino acid derivatives and other non-proteinogenic amino acid structures.
• Material Science Precursor: Potential use in synthesizing specialized monomers for advanced polymers and functional materials.

Basic Information

Product Name	Ethyl 3-(Benzyloxycarbonylamino)-3-Methylbutanoate
CAS No.	1381947-21-2
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	Ethyl 3-[[(Benzyloxy)carbonyl]amino]-3-methylbutanoate; 3-[(Benzyloxycarbonyl)amino]-3-methylbutyric Acid Ethyl Ester; Cbz-3-Amino-3-methylbutyric Acid Ethyl Ester; Z-3-Amino-3-methylbutyric Acid Ethyl Ester; Ethyl 3-(N-Cbz-amino)-3-methylbutyrate; Ethyl 3-[(Cbz-amino)]-3-methylbutanoate; 3-(Benzyloxycarbonylamino)-3-methyl-butanoic acid ethyl ester; Butanoic acid, 3-[[(phenylmethoxy)carbonyl]amino]-3-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Benzyloxycarbonylamino)-3-Methylbutanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.