Description

6-Oxa-1-Azaspiro[3.3]Heptane Oxalate(2:1) is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is valued for its unique spirocyclic structure, which is critical for modulating the physicochemical and pharmacokinetic properties of active pharmaceutical ingredients (APIs). It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small molecule therapeutics, particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging its heterocyclic scaffold.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Serves as a valuable linker or core component in the design of bifunctional molecules for targeted protein degradation.
• Ligand & Catalyst Development: Employed in the creation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential precursor for the synthesis of specialized polymers and functional materials with unique properties.

Basic Information

Product Name	6-Oxa-1-Azaspiro[3.3]Heptane Oxalate(2:1)
CAS No.	1380571-72-1
Molecular Formula	C8H12N2O5
Molecular Weight	216.19 g/mol
Synonyms	6-Oxa-1-azaspiro[3.3]heptane oxalate (2:1); 1-Aza-6-oxaspiro[3.3]heptane oxalate; Azetidine, 1-(oxiranylmethyl)-, oxalate (2:1); 1-(Oxiran-2-ylmethyl)azetidine oxalate salt; Oxetan-3-ylmethylazetidine oxalate; Spiro[3.3]heptane-1,6-diamine derivative; 1380571-72-1
EINECS	Contact for details

Quality Control

Our 6-Oxa-1-Azaspiro[3.3]Heptane Oxalate(2:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available for every shipment. We support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.