Description

1,1,1-Trifluoro-3-Oxetanyl Methanesulfonic Acid Ester is a high-value fluorinated oxetane derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in introducing the trifluoro-oxetane moiety, which is prized for enhancing the metabolic stability, lipophilicity, and overall physicochemical profile of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for incorporating the trifluoromethyl-oxetane group into drug candidates to improve their pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated oxetane structure can contribute to efficacy and environmental profile.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with unique surface properties, chemical resistance, or optical characteristics.
• Liquid Crystal & OLED Materials: Employed in the development of fluorinated components for electronic display and lighting technologies.
• Lithography & Photoresists: Potential application as a precursor in the formulation of advanced photoresists for semiconductor manufacturing.
• Organic Synthesis Reagent: Acts as an alkylating agent or protecting group reagent in complex multi-step synthetic routes.

Basic Information

Product Name	1,1,1-Trifluoro-3-Oxetanyl Methanesulfonic Acid Ester
CAS No.	1379585-89-3
Molecular Formula	C5H5F3O4S
Molecular Weight	218.15 g/mol
Synonyms	3-(Trifluoromethyl)oxetan-3-yl methanesulfonate; 1,1,1-Trifluoro-3-oxetanyl methanesulfonate; 3-(Trifluoromethyl)-3-oxetanyl methanesulfonate; 3-Methanesulfonyloxy-3-(trifluoromethyl)oxetane; Trifluoro-oxetane mesylate ester; Oxetane, 3-[(methylsulfonyl)oxy]-3-(trifluoromethyl)-; TOMME; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-3-Oxetanyl Methanesulfonic Acid Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.